THE TWELVE NEW RUNES

Ritual runes (the trigger half; each gives Offering when it fires):
• Amn (Thorned): Deal Thorns Damage. · gains 4 Offering
• Eth (Prudent): Avoid spending Primary Resource while fighting for 5 seconds. · gains 600 Offering
• Mal (Prime): Invoke your Prime Evil power · gains 666 Offering
• Ort (Elemental): Deal Non-Physical Direct Damage · gains 1 Offering
• Tal (Winnowing): Deal Damage over Time · gains 3 Offering

Invocation runes (the payload half; each spends Offering):
• Ber (Verdict): Lucky Hit: Your next 5 skills have up to a 10% Chance to deliver a Crushing Blow. · requires 200 Offering · overflow: Gain Multiple Stacks
• Ist (Evil): Invoke your Prime Evil power. · requires 1000 Offering
• Ith (Power): Gain +5 Weapon Damage for 5 seconds, up to +125. · requires 175 Offering · overflow: Gain Multiple Stacks
• Lo (Lethality): Gain 25% Deadly Strike Chance for 10 seconds. · requires 600 Offering · overflow: Increased Duration
• Ral (Greed): Gain 250% Gold Find for 7 seconds. · requires 400 Offering
• Sol (Bulwark): Gain 15% Damage Reduction for 6 seconds. · requires 350 Offering
• Tir (Harvest): Gain +2 Primary Resource on Kill for 8 seconds, up to +8. · requires 300 Offering · overflow: Gain Multiple Stacks

All twelve are Unique-rarity runes, new in Season 15. One Ritual plus one Invocation in a two-socket item still makes a runeword the way it has since Season 6. The runes Jah, Vex, Ohm, Thul, Lum and Eom already existed in Diablo IV, and the recipes below use them too.

RUNE CRAFTING (HORADRIC CUBE)

Fourteen hidden cube recipes upgrade a rune into the next one up the ladder: Tir → Eth → Ith → Tal → Ral → Ort → Thul → Amn → Sol → Mal → Ist → Vex → Ohm → Lo → Ber → Jah.

THE NINETEEN RUNEWORDS

These are Diablo IV items, new in Season 15. Each one is a Horadric Cube recipe: put a base item of the right type and the listed runes into the cube and it makes a Unique item with the runeword's name. The recipe shows as "???" until the last rune is in. The item keeps the base's item power and prints the runes on its runeword line. The rune order for each is the same order the original Diablo II recipe used (Enigma is Jah, Ith, Ber in both games).

Reading each entry: the runes go into the cube in the order written, with the item named under them; "you get" is the item's special power where it has one; the stat lines are the fixed lines the item carries, numbers included where the records fix them (a line with no number scales with the base's item power). Nothing here is typed: every word and number is read out of the 3.2.1 game files.

ANCIENT'S PLEDGE
Runes, in order: Ral, Ort, Tal
Put them in: one of: Focus, Shield, Totem
Stat lines:
• x35% All Damage Multiplier
• +35% Cold Resistance
• +35% Fire Resistance
• +35% Lightning Resistance
• +35% Poison Resistance
• 35% Damage Reduction

CALL TO ARMS
Runes, in order: Amn, Ral, Mal, Ist, Ohm
Put them in: one of: Axe, Dagger, Flail, Focus, Mace, Scythe, Sword, Totem, Wand
You get: While affected by a Shout Skill gain: +5 Ranks to all Skills; +15% Maximum Life; +15%[x] Maximum Primary Resource
Stat lines:
• +200-250 Weapon Damage
• +1 to All Skills
• x40% All Damage Multiplier
• +5 to Shout Skills
• +40% Attack Speed

EDGE
Runes, in order: Tir, Tal, Amn
Put them in: one of: Bow, Crossbow, Glaive, Polearm, Quarterstaff, Staff, Two-Handed Axe, Two-Handed Mace, Two-Handed Scythe, Two-Handed Sword
Stat lines:
• +17.5% Attack Speed
• +100% Damage to Demons
• Lucky Hit: Up to a 40% Chance to Deal Poisoning Damage over 10 seconds
• All Stats
• Thorns
• +100% Damage to Undead

ENIGMA
Runes, in order: Jah, Ith, Ber
Put them in: a Chest Armor
You get: Your Evade is now Sorcerer's Teleport and costs 33 Primary Resource.
Stat lines:
• +2 to All Skills
• +45% Movement Speed
• 12% Damage Reduction
• 40% Maximum Life
• Armor

GRIEF
Runes, in order: Eth, Tir, Lo, Mal, Ral
Put them in: one of: Berserker Axe, Phase Blade
You get: Your direct damage inflicts 40% bonus Poisoning damage over 5 seconds.
Stat lines:
• +750-1000 Weapon Damage
• +20% Deadly Strike Chance
• +30-40% Attack Speed
• +100% Damage to Demons
• +2 Primary Resource On Kill

HOLY THUNDER
Runes, in order: Eth, Ral, Ort, Tal
Put them in: one of: Flail, Mace
You get: You emit Crackling Energy. Enemies damaged by Crackling Energy take 20-35%[x] increased Holy, Fire, Lightning, and Physical damage from you for 3 seconds.
Stat lines:
• +35% Lightning Resistance
• x50% All Damage Multiplier
• +20% Lucky Hit Chance

INFINITY
Runes, in order: Ber, Mal, Ber, Ist
Put them in: one of: Bow, Crossbow, Glaive, Polearm, Quarterstaff, Staff, Two-Handed Axe, Two-Handed Mace, Two-Handed Scythe, Two-Handed Sword
You get: 50% Chance to unleash a Rank 10 Sorcerer Chain Lightning when you kill an enemy. You gain the Rank 11 passive of Druid's Cyclone Armor. Close enemies are Vulnerable and take 62.5%[x] more damage from you.
Stat lines:
• +17.5% Movement Speed
• Maximum Life
• 50-100% Gold Drop Rate

INSIGHT
Runes, in order: Ral, Tir, Tal, Sol
Put them in: one of: Bow, Crossbow, Glaive, Polearm, Quarterstaff, Staff, Two-Handed Scythe
Stat lines:
• +17.5% Attack Speed
• Critical Strike Chance
• Weapon Damage
• All Stats
• x100% Critical Strike Damage Multiplier

KING'S GRACE
Runes, in order: Amn, Ral, Thul
Put them in: one of: Flail, Mace, Sword
Stat lines:
• +100% Damage to Demons
• +100% Damage to Undead
• Life On Hit
• +50% Lucky Hit Chance
• x75% All Damage Multiplier

LEAF
Runes, in order: Tir, Ral
Put them in: a Staff
Stat lines:
• +2 Primary Resource On Kill
• +17.5% Cold Resistance
• 10% Resource Generation

LORE
Runes, in order: Ort, Sol
Put them in: a Helm
Stat lines:
• +2 to All Skills
• +25 Maximum Resource
• 10% Damage Reduction
• Lightning Resistance
• +2 Primary Resource On Kill
• Armor

PATTERN
Runes, in order: Tal, Ort, Thul
Put them in: a Dagger
Stat lines:
• x50% All Damage Multiplier
• +10% All Stats
• Lucky Hit: Up to a 40% Chance to Deal Poisoning Damage over 10 seconds
• +10-20% Critical Strike Chance
• Resistance to All Elements

PHOENIX
Runes, in order: Vex, Vex, Lo, Jah
Put them in: one of: Axe, Dagger, Flail, Focus, Mace, Scythe, Shield, Sword, Totem, Wand
You get (Axe, Dagger, Flail, Focus, Mace, Scythe, Sword, Totem, Wand): When you level up, unleash a Rank 40 Ring of Fire. Lucky Hit: Attacks have up to a 15-30% chance to unleash a Rank 22 Fire Spear.
Stat lines (Axe, Dagger, Flail, Focus, Mace, Scythe, Sword, Totem, Wand):
• Life On Kill
• Lucky Hit: Up to a 40% Chance to Deal Fire Damage
• +20% Deadly Strike Chance
• x50% All Damage Multiplier
You get (Shield): When you level up, unleash a Rank 40 Ring of Fire. Lucky Hit: Attacks have up to a 15-30% chance to unleash a Rank 22 Fire Spear.
Stat lines (Shield):
• Life On Kill
• +35% Fire Resistance
• +20% Deadly Strike Chance
• x50% All Damage Multiplier
• 10% Damage Reduction

PRUDENCE
Runes, in order: Mal, Tir
Put them in: a Chest Armor
Stat lines:
• +500 Resistance to All Elements
• 10% Damage Reduction
• 25% Impairment Reduction
• +20-35% Total Armor
• +2 Primary Resource On Kill
• 10% Dodge Chance

RAIN
Runes, in order: Ort, Mal, Ith
Put them in: a Chest Armor
You get: Lucky Hit: Attacks have up to a 15-30% chance to unleash a Rank 15 Druid Tornado. 50% Chance to unleash a Rank 15 Druid Cyclone Armor whenever you Dodge.
Stat lines:
• +25-40 Maximum Resource
• +5 to Nature Magic Skills
• 10% Damage Reduction
• +35% Lightning Resistance
• 10% Dodge Chance

SPIRIT
Runes, in order: Tal, Thul, Ort, Amn
Put them in: one of: Axe, Dagger, Flail, Focus, Mace, Scythe, Shield, Sword, Totem, Wand
Stat lines (Axe, Dagger, Flail, Focus, Mace, Scythe, Sword, Totem, Wand):
• +5 to All Skills
• +25-35% Attack Speed
• x50% All Damage Multiplier
• +20-56 Maximum Resource
• 50% Impairment Reduction
Stat lines (Shield):
• Maximum Life
• +5 to All Skills
• +25-35% Attack Speed
• +20-56 Maximum Resource
• 50% Impairment Reduction

STEALTH
Runes, in order: Tal, Eth
Put them in: a Chest Armor
You get: Your Evade is now Sorcerer's Teleport and costs 33 Primary Resource.
Stat lines:
• Maximum Life
• +25% Attack Speed
• 25% Impairment Reduction
• 15% Resource Generation
• +25% Movement Speed
• 15% Damage Reduction

STRENGTH
Runes, in order: Amn, Tir
Put them in: one of: Axe, Dagger, Flail, Focus, Mace, Scythe, Sword, Totem, Wand
Stat lines:
• x50% All Damage Multiplier
• +10% Strength
• Maximum Life
• Life On Hit
• +2 Primary Resource On Kill

ZEPHYR
Runes, in order: Ort, Eth
Put them in: one of: Bow, Crossbow
You get: Unleash a Dust Devil whenever you Dodge.
Stat lines:
• 12.5% Dodge Chance
• +12.5% Attack Speed
• +12.5% Movement Speed
• x62.5% All Damage Multiplier
• Lucky Hit: Up to a 40% Chance to Deal Lightning Damage